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Characterization of Amikacin Drug Exposure and Nephrotoxicity in an Animal Model
Despite excellent in vitro activity, aminoglycosides are used conservatively to treat multidrug-resistant bacterial infections due to their associated nephrotoxicity. Aminoglycosides are known to accumulate in the kidneys, but the quantitative relationship between drug exposures and nephrotoxicity i...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449196/ https://ncbi.nlm.nih.gov/pubmed/32571819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00859-20 |
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