Role of Renal Drug Exposure in Polymyxin B-Induced Nephrotoxicity

Despite dose-limiting nephrotoxic potentials, polymyxin B has reemerged as the last line of therapy against multidrug-resistant Gram-negative bacterial infections. However, the handling of polymyxin B by the kidneys is still not thoroughly understood. The objectives of this study were to evaluate th...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Manchandani, Pooja, Zhou, Jian, Babic, Jessica T., Ledesma, Kimberly R., Truong, Luan D., Tam, Vincent H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365704/
https://ncbi.nlm.nih.gov/pubmed/28096166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02391-16
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