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Pharmacokinetics and Renal Disposition of Polymyxin B in an Animal Model

The increasing prevalence of multidrug-resistant Gram-negative infections has led to the resurgence of systemic polymyxin B, but little is known about its pharmacokinetics. The objective of this study was to characterize the pharmacokinetics and renal disposition of polymyxin B. Eight female Sprague...

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Библиографические подробности
Главные авторы: Abdelraouf, Kamilia, He, Jie, Ledesma, Kimberly R., Hu, Ming, Tam, Vincent H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486600/
https://ncbi.nlm.nih.gov/pubmed/22908162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01333-12
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