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Pharmacokinetics and Renal Disposition of Polymyxin B in an Animal Model

The increasing prevalence of multidrug-resistant Gram-negative infections has led to the resurgence of systemic polymyxin B, but little is known about its pharmacokinetics. The objective of this study was to characterize the pharmacokinetics and renal disposition of polymyxin B. Eight female Sprague...

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Detalhes bibliográficos
Main Authors: Abdelraouf, Kamilia, He, Jie, Ledesma, Kimberly R., Hu, Ming, Tam, Vincent H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486600/
https://ncbi.nlm.nih.gov/pubmed/22908162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01333-12
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