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Pharmacokinetics and efficacy of liposomal polymyxin B in a murine pneumonia model()
Polymyxin B (PB) is increasingly used as the last treatment for multidrug-resistant (MDR) Gram-negative bacterial infections. In this study, serum and epithelial lining fluid (ELF) pharmacokinetics and the efficacy of a PB liposomal formulation were investigated. Two groups of 24 Swiss Webster mice...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849129/ https://ncbi.nlm.nih.gov/pubmed/24016799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2013.07.009 |
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