Pharmacokinetics and efficacy of liposomal polymyxin B in a murine pneumonia model()

Polymyxin B (PB) is increasingly used as the last treatment for multidrug-resistant (MDR) Gram-negative bacterial infections. In this study, serum and epithelial lining fluid (ELF) pharmacokinetics and the efficacy of a PB liposomal formulation were investigated. Two groups of 24 Swiss Webster mice...

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Detaylı Bibliyografya
Asıl Yazarlar: He, Jie, Abdelraouf, Kamilia, Ledesma, Kimberly R., Chow, Diana S.-L., Tam, Vincent H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849129/
https://ncbi.nlm.nih.gov/pubmed/24016799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2013.07.009
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