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Pharmacokinetics and Renal Disposition of Polymyxin B in an Animal Model

The increasing prevalence of multidrug-resistant Gram-negative infections has led to the resurgence of systemic polymyxin B, but little is known about its pharmacokinetics. The objective of this study was to characterize the pharmacokinetics and renal disposition of polymyxin B. Eight female Sprague...

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Bibliographic Details
Main Authors: Abdelraouf, Kamilia, He, Jie, Ledesma, Kimberly R., Hu, Ming, Tam, Vincent H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486600/
https://ncbi.nlm.nih.gov/pubmed/22908162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01333-12
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