In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection

Herpes simplex virus type 2 (HSV-2) causes recurrent lesions in the anogenital area that may be transmitted through sexual encounters. Nucleoside analogs, such as acyclovir (ACV), are currently prescribed clinically to curb this infection. However, in some cases, reduced efficacy has been observed d...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Hopkins, James, Yadavalli, Tejabhiram, Suryawanshi, Rahul, Qatanani, Farreh, Volety, Ipsita, Koganti, Ram, Iqbal, Aqsa, Shukla, Deepak
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449169/
https://ncbi.nlm.nih.gov/pubmed/32601167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00245-20
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