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Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV

Middle East respiratory syndrome coronavirus (MERS-CoV) is a WHO priority pathogen for which vaccines are urgently needed. Using an immune-focusing approach, we created self-assembling particles multivalently displaying critical regions of the MERS-CoV spike protein ─fusion peptide, heptad repeat 2,...

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Detaylı Bibliyografya
Yayımlandı:Emerg Microbes Infect
Asıl Yazarlar: Okba, Nisreen M. A., Widjaja, Ivy, van Dieren, Brenda, Aebischer, Andrea, van Amerongen, Geert, de Waal, Leon, Stittelaar, Koert J., Schipper, Debby, Martina, Byron, van den Brand, Judith M. A., Beer, Martin, Bosch, Berend-Jan, Haagmans, Bart L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448924/
https://ncbi.nlm.nih.gov/pubmed/32471334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1760735
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