Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV

Middle East respiratory syndrome coronavirus (MERS-CoV) is a WHO priority pathogen for which vaccines are urgently needed. Using an immune-focusing approach, we created self-assembling particles multivalently displaying critical regions of the MERS-CoV spike protein ─fusion peptide, heptad repeat 2,...

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Bibliographic Details
Published in:Emerg Microbes Infect
Main Authors: Okba, Nisreen M. A., Widjaja, Ivy, van Dieren, Brenda, Aebischer, Andrea, van Amerongen, Geert, de Waal, Leon, Stittelaar, Koert J., Schipper, Debby, Martina, Byron, van den Brand, Judith M. A., Beer, Martin, Bosch, Berend-Jan, Haagmans, Bart L.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448924/
https://ncbi.nlm.nih.gov/pubmed/32471334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1760735
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