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Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions

ABSTRACT: Metabolites produced via traditional biochemical processes affect intracellular communication, inflammation, and malignancy. Unexpectedly, acetyl-CoA, α-ketoglutarate and palmitic acid, which are chemical species of reactions catalyzed by highly abundant, gigantic enzymatic complexes, dubb...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Skalidis, Ioannis, Tüting, Christian, Kastritis, Panagiotis L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448341/
https://ncbi.nlm.nih.gov/pubmed/32843078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00631-9
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