Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch

Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the impossibility of distinguishing integrated from episomal tr...

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Kumamoto, Takuma, Maurinot, Franck, Barry-Martinet, Raphaëlle, Vaslin, Célia, Vandormael-Pournin, Sandrine, Le, Mickaël, Lerat, Marion, Niculescu, Dragos, Cohen-Tannoudji, Michel, Rebsam, Alexandra, Loulier, Karine, Nedelec, Stéphane, Tozer, Samuel, Livet, Jean
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447981/
https://ncbi.nlm.nih.gov/pubmed/32559415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.05.038
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