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Heterologous expression of high-activity cytochrome P450 in mammalian cells
The evaluation of Cytochrome P450 (CYP) enzymatic activity is essential to estimate drug pharmacokinetics. Numerous CYP allelic variants have been identified; the functional characterisation of these variants is required for their application in precision medicine. Results from heterologous expressi...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7447777/ https://ncbi.nlm.nih.gov/pubmed/32843676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71035-5 |
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