Deletion of the von Hippel-Lindau Gene in Hemangioblasts Causes Hemangioblastoma-like Lesions in Murine Retina

von Hippel-Lindau (VHL) disease is an autosomal-dominant tumor predisposition syndrome characterized by the development of highly vascularized tumors and cysts. LOH of the VHL gene results in aberrant upregulation of hypoxia-inducible factors (HIF) and has been associated with tumor formation. Heman...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Wang, Herui, Shepard, Matthew J., Zhang, Chao, Dong, Lijin, Walker, Dyvon, Guedez, Liliana, Park, Stanley, Wang, Yujuan, Chen, Shida, Pang, Ying, Zhang, Qi, Gao, Chun, Wong, Wai T., Wiley, Henry, Pacak, Karel, Chew, Emily Y., Zhuang, Zhengping, Chan, Chi-Chao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446935/
https://ncbi.nlm.nih.gov/pubmed/29301791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1718
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk