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Alpha-crystallin mutations alter lens metabolites in mouse models of human cataracts
Cataracts are a major cause of blindness worldwide and commonly occur in individuals over 70 years old. Cataracts can also appear earlier in life due to genetic mutations. The lens proteins, αA- and αB-crystallins, are chaperone proteins that have important roles maintaining protein solubility to pr...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7446835/ https://ncbi.nlm.nih.gov/pubmed/32833997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238081 |
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