Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer

PURPOSE: Patients with castration-resistant prostate cancer (CRPC) receive second-generation androgen-deprivation therapy, but frequently experience relapse or do not respond. Understanding the genetic mechanisms of resistance will help to identify strategies and biomarkers that are essential for th...

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Vydáno v:JCO Precis Oncol
Hlavní autoři: Han, G. Celine, Hwang, Justin, Wankowicz, Stephanie A.M., Zhang, Zhenwei, Liu, David, Cibulskis, Carrie, Gaviola, Glenn C., Ghazikhanian, Varand, McKay, Rana R., Bubley, Glenn J., Carter, Scott L., Balk, Steven P., Hahn, William C., Taplin, Mary-Ellen, Van Allen, Eliezer M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2017
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446377/
https://ncbi.nlm.nih.gov/pubmed/32913968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00140
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