Prioritizing Crohn’s disease genes by integrating association signals with gene expression implicates monocyte subsets: Crohn’s disease gene prioritization

Genome-wide association studies have identified approximately 170 loci associated with Crohn’s disease (CD), and defining which genes drive these association signals is a major challenge. The primary aim of this study was to define which CD-locus genes are most likely to be disease-related. We devel...

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發表在:Genes Immun
Main Authors: Gettler, Kyle, Giri, Mamta, Kenigsberg, Ephraim, Martin, Jerome, Chuang, Ling-Shiang, Hsu, Nai-Yun, Denson, Lee A., Hyams, Jeffrey S., Griffiths, Anne, Noe, Joshua D., Crandall, Wallace V., Mack, David R., Kellermayer, Richard, Abraham, Clara, Hoffman, Gabriel, Kugathasan, Subra, Cho, Judy H.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446136/
https://ncbi.nlm.nih.gov/pubmed/30692607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-019-0059-y
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