Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

Detection of lymphocytes that target tumor-specific mutant neoantigens—derived from products encoded by mutated genes in the tumor—is mostly limited to tumor-resident lymphocytes(1,2), but whether these lymphocytes often occur in the circulation is unclear. We recently reported that intratumoral exp...

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Vydáno v:Nat Med
Hlavní autoři: Gros, Alena, Parkhurst, Maria R, Tran, Eric, Pasetto, Anna, Robbins, Paul F, Ilyas, Sadia, Prickett, Todd D, Gartner, Jared J, Crystal, Jessica S, Roberts, Ilana M, Trebska-McGowan, Kasia, Wunderlich, John R, Yang, James C, Rosenberg, Steven A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446107/
https://ncbi.nlm.nih.gov/pubmed/26901407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4051
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