Transcriptional and Functional Analysis of CD1c(+) Human Dendritic Cells Identifies a CD163(+) Subset Priming CD8(+)CD103(+) T Cells

Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here, we identified circulating CD88(−)CD1c(+)CD163(+) DCs (called DC3s) as immediate precursors of inflammatory C...

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Publicat a:Immunity
Autors principals: Bourdely, Pierre, Anselmi, Giorgio, Vaivode, Kristine, Ramos, Rodrigo Nalio, Missolo-Koussou, Yoann, Hidalgo, Sofia, Tosselo, Jimena, Nuñez, Nicolas, Richer, Wilfrid, Vincent-Salomon, Anne, Saxena, Alka, Wood, Kristie, Lladser, Alvaro, Piaggio, Eliane, Helft, Julie, Guermonprez, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445430/
https://ncbi.nlm.nih.gov/pubmed/32610077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.06.002
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