Cross-presenting CD103(+) dendritic cells are protected from influenza virus infection

CD8(+) cytotoxic T cells are critical for viral clearance from the lungs upon influenza virus infection. The contribution of antigen cross-presentation by DCs to the induction of anti-viral cytotoxic T cells remains controversial. Here, we used a recombinant influenza virus expressing a nonstructura...

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Bibliografiske detaljer
Main Authors: Helft, Julie, Manicassamy, Balaji, Guermonprez, Pierre, Hashimoto, Daigo, Silvin, Aymeric, Agudo, Judith, Brown, Brian D., Schmolke, Mirco, Miller, Jennifer C., Leboeuf, Marylene, Murphy, Kenneth M., García-Sastre, Adolfo, Merad, Miriam
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484433/
https://ncbi.nlm.nih.gov/pubmed/23041628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60659
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