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Targeting of intracellular Ca(2+) stores as a therapeutic strategy against age-related neurotoxicities

Calcium dysregulation often underlies pathologies associated with aging and age-associated neurodegenerative diseases. Cells express a unique pattern of Ca(2+) channels and pumps geared to fulfill specific physiological requirements and there is a decline in the fidelity of these processes with age...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Goldberg, Joshua, Currais, Antonio, Ates, Gamze, Huang, Ling, Shokhirev, Maxim, Maher, Pamela, Schubert, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445274/
https://ncbi.nlm.nih.gov/pubmed/32884834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-020-00048-1
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