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Elevating acetyl-CoA levels reduces aspects of brain aging

Because old age is the greatest risk factor for dementia, a successful therapy will require an understanding of the physiological changes that occur in the brain with aging. Here, two structurally distinct Alzheimer's disease (AD) drug candidates, CMS121 and J147, were used to identify a unique...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Currais, Antonio, Huang, Ling, Goldberg, Joshua, Petrascheck, Michael, Ates, Gamze, Pinto-Duarte, António, Shokhirev, Maxim N, Schubert, David, Maher, Pamela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882557/
https://ncbi.nlm.nih.gov/pubmed/31742554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47866
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