Phosphorylation of PRAS40 contributes to the activation of the PI3K/AKT/mTOR signaling pathway and the inhibition of autophagy following status epilepticus in rats

Status epilepticus (SE) is a neurological disorder associated with high morbidity and mortality rates, and is often difficult to treat. Moreover, the underlying mechanism of SE remains unknown. The lithium-pilocarpine model is a validated animal model that can reproduce the main clinical and neuropa...

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Vydáno v:Exp Ther Med
Hlavní autoři: Lin, Junyi, Fang, Youxin, Zhang, Mingchang, Wang, Xiang, Li, Liliang, He, Meng, Xue, Aimin, Zhu, Keming, Shen, Yiwen, Li, Beixu
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444373/
https://ncbi.nlm.nih.gov/pubmed/32855714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9085
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