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Regulatory T cells suppress Th17 cell Ca(2+) signaling in the spinal cord during murine autoimmune neuroinflammation

T lymphocyte motility and interaction dynamics with other immune cells are vital determinants of immune responses. Regulatory T (Treg) cells prevent autoimmune disorders by suppressing excessive lymphocyte activity, but how interstitial motility patterns of Treg cells limit neuroinflammation is not...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Othy, Shivashankar, Jairaman, Amit, Dynes, Joseph L., Dong, Tobias X., Tune, Cornelia, Yeromin, Andriy V., Zavala, Angel, Akunwafo, Chijioke, Chen, Fangyi, Parker, Ian, Cahalan, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443932/
https://ncbi.nlm.nih.gov/pubmed/32732436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006895117
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