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Optimizing immunization protocols to elicit broadly neutralizing antibodies

Natural infections and vaccination with a pathogen typically stimulate the production of potent antibodies specific for the pathogen through a Darwinian evolutionary process known as affinity maturation. Such antibodies provide protection against reinfection by the same strain of a pathogen. A highl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sprenger, Kayla G., Louveau, Joy E., Murugan, Pranav M., Chakraborty, Arup K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443869/
https://ncbi.nlm.nih.gov/pubmed/32747563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919329117
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