M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

BACKGROUND: The immunological microenvironment of primary high-grade serous carcinomas (HGSCs) has a major impact on disease outcome. Conversely, little is known on the microenvironment of metastatic HGSCs and its potential influence on patient survival. Here, we explore the clinical relevance of th...

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Détails bibliographiques
Publié dans:J Immunother Cancer
Auteurs principaux: Hensler, Michal, Kasikova, Lenka, Fiser, Karel, Rakova, Jana, Skapa, Petr, Laco, Jan, Lanickova, Tereza, Pecen, Ladislav, Truxova, Iva, Vosahlikova, Sarka, Moserova, Irena, Praznovec, Ivan, Drochytek, Vit, Rehackova, Martina, Brtnicky, Tomas, Rob, Lukas, Benes, Vladimir, Pistolic, Jelena, Sojka, Ludek, Ryska, Ales, Sautes-Fridman, Catherine, Fridman, Wolf Herve, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2020
Sujets:
Immunotherapy Biomarkers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443306/
https://ncbi.nlm.nih.gov/pubmed/32819974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000979
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