Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

High hydrostatic pressure (HHP) promotes key characteristics of immunogenic cell death (ICD), in thus far resembling immunogenic chemotherapy and ionizing irradiation. Here, we demonstrate that cancer cells succumbing to HHP induce CD4(+) and CD8(+) T cell-dependent protective immunity in vivo. More...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Moserova, Irena, Truxova, Iva, Garg, Abhishek D., Tomala, Jakub, Agostinis, Patrizia, Cartron, Pierre Francois, Vosahlikova, Sarka, Kovar, Marek, Spisek, Radek, Fucikova, Jitka
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283635/
https://ncbi.nlm.nih.gov/pubmed/28197379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1258505
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