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Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

High hydrostatic pressure (HHP) promotes key characteristics of immunogenic cell death (ICD), in thus far resembling immunogenic chemotherapy and ionizing irradiation. Here, we demonstrate that cancer cells succumbing to HHP induce CD4(+) and CD8(+) T cell-dependent protective immunity in vivo. More...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Moserova, Irena, Truxova, Iva, Garg, Abhishek D., Tomala, Jakub, Agostinis, Patrizia, Cartron, Pierre Francois, Vosahlikova, Sarka, Kovar, Marek, Spisek, Radek, Fucikova, Jitka
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283635/
https://ncbi.nlm.nih.gov/pubmed/28197379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1258505
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