Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

High hydrostatic pressure (HHP) promotes key characteristics of immunogenic cell death (ICD), in thus far resembling immunogenic chemotherapy and ionizing irradiation. Here, we demonstrate that cancer cells succumbing to HHP induce CD4(+) and CD8(+) T cell-dependent protective immunity in vivo. More...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Moserova, Irena, Truxova, Iva, Garg, Abhishek D., Tomala, Jakub, Agostinis, Patrizia, Cartron, Pierre Francois, Vosahlikova, Sarka, Kovar, Marek, Spisek, Radek, Fucikova, Jitka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283635/
https://ncbi.nlm.nih.gov/pubmed/28197379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1258505
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