ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway

ELABELA (ELA), a 32-residue hormone peptide abundantly expressed in adult kidneys, has been identified as a novel endogenous ligand for APJ/Apelin receptor. The aim of this study was to investigate the role of ELA in deoxycorticosterone acetate (DOCA)/salt-induced hypertension and further explore th...

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Publicado no:Cell Death Dis
Main Authors: Chen, Zhida, Wu, Chunying, Liu, Yuting, Li, Haonan, Zhu, Yeyan, Huang, Cailing, Lin, Huangbo, Qiao, Qiao, Huang, Mengming, Zhu, Qing, Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443189/
https://ncbi.nlm.nih.gov/pubmed/32829380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02912-0
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