Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan

Genetic polymorphism in cytochrome P450 (CYP) monooxygenase genes is an important source of interindividual variability of drug response. CYP enzyme activities may change as a result of such polymorphisms which then, may affect drug metabolism. This would result in a change in the severity and frequ...

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Udgivet i:PeerJ
Main Authors: Ahmed, Sagheer, Altaf, Nadeem, Ejaz, Mahnoor, Zulfiqar, Zaira, Janjua, Kholood, Festila, Dana, Cristina, Nicula
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443092/
https://ncbi.nlm.nih.gov/pubmed/32879799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9721
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