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Inter-ethnic genetic variations and novel variant identification in the partial sequences of CYP2B6 gene in Pakistani population

BACKGROUND: Some single nucleotide polymorphisms (SNPs) in the cytochrome P450 (CYP)2B6 gene lead to decreased enzyme activity and have an impact on drug metabolism. The present study was designed to investigate the patterns of genetic distinction across a hypervariable region of the CYP2B6 gene, kn...

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Pubblicato in:PeerJ
Autori principali: Ahmed, Sagheer, Khan, Hizbullah, Khan, Asifullah, Bangash, Muhammad Hanif, Hussain, Abrar, Qayum, Mughal, Hamdard, Mohammad Hamid
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312491/
https://ncbi.nlm.nih.gov/pubmed/34386299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11149
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