Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan

Genetic variation in cytochrome P450 (CYP) 2C9 is known to cause significant inter-individual differences in drug response and adverse effects. The frequencies of CYP2C9*2 and CYP2C9*3, both of which are responsible for the low activity of the enzyme, are not known in the Pakistani population. There...

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Udgivet i:Sci Rep
Main Authors: Ahmed, Sagheer, Altaf, Nadeem, Ejaz, Mahnoor, Altaf, Aisha, Amin, Aneela, Janjua, Kholood, Khan, Arif Ullah, Imran, Imran, Khan, Saeed
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652876/
https://ncbi.nlm.nih.gov/pubmed/33168919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76366-x
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