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Is the p3 (Aβ17–40, Aβ17–42) peptide relevant to the pathology of Alzheimer’s Disease?

Despite the vast heterogeneity of amyloid plaques isolated from the brains of those with Alzheimer’s Disease (AD), the basis of the Amyloid Cascade Hypothesis (ACH) targets a single peptide, the amyloid-β (Aβ) peptide. The countless therapeutic efforts targeting the production and aggregation of thi...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Kuhn, Ariel J., Raskatov, Jevgenij
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443050/
https://ncbi.nlm.nih.gov/pubmed/32176648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191201
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