Relevance of Aβ42/40 Ratio for Detection of Alzheimer Disease Pathology in Clinical Routine: The PLM(R) Scale

Background: Cerebrospinal fluid (CSF) biomarkers (Aβ peptides and tau proteins) improved the diagnosis of Alzheimer’s disease (AD) in research and clinical settings. We previously described the PLM-scale (Paris-Lille-Montpellier study), which combines Aβ42, tau, and phosphorylated ptau(181) biomarke...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Lehmann, Sylvain, Delaby, Constance, Boursier, Guilaine, Catteau, Cindy, Ginestet, Nelly, Tiers, Laurent, Maceski, Aleksandra, Navucet, Sophie, Paquet, Claire, Dumurgier, Julien, Vanmechelen, Eugeen, Vanderstichele, Hugo, Gabelle, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985301/
https://ncbi.nlm.nih.gov/pubmed/29892221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00138
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