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Use of Paramagnetic (19)F NMR to Monitor Domain Movement in a Glutamate Transporter

In proteins where conformational changes are functionally important, the number of accessible states and their dynamics are often difficult to establish. Here we describe a novel (19)F-NMR spectroscopy approach to probe dynamics of large membrane proteins. We labeled a glutamate transporter homologu...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Huang, Yun, Wang, Xiaoyu, Lv, Guohua, Razavi, Asghar M., Huysmans, Gerard H. M., Weinstein, Harel, Bracken, Clay, Eliezer, David, Boudker, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442671/
https://ncbi.nlm.nih.gov/pubmed/32514183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0561-6
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