Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder

Kinetic properties of membrane transporters are typically poorly defined because high-resolution functional assays analogous to single-channel recordings are lacking. Here, we measure single-molecule transport kinetics of a glutamate transporter homolog from Pyrococcus horikoshii, Glt(Ph), using flu...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Ciftci, Didar, Huysmans, Gerard H. M., Wang, Xiaoyu, He, Changhao, Terry, Daniel, Zhou, Zhou, Fitzgerald, Gabriel, Blanchard, Scott C., Boudker, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259943/
https://ncbi.nlm.nih.gov/pubmed/32523985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1949
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