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Fe(2+)-Mediated Activation of BK(Ca) Channels by Rapid Photolysis of CORM-S1 Releasing CO and Fe(2+)
Heme catabolism by heme oxygenase (HO) with a decrease in intracellular heme concentration and a concomitant local release of CO and Fe(2+) has potential to regulate BK(Ca) channels. Here we show that the iron-based photolabile CO-releasing molecule CORM-S1 [dicarbonyl-bis(cysteamine)iron(II)] co-re...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442670/ https://ncbi.nlm.nih.gov/pubmed/32667185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00282 |
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