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HDAC10 Regulates Cancer Stem-like Cell Properties in KRAS-driven Lung Adenocarcinoma

Activation of oncogenic KRAS is the most common driving event in lung adenocarcinoma development. Despite the existing rationale for targeting activated KRAS and its downstream effectors, the failure of clinical trials to date indicates that the mechanism of KRAS-driven malignancy remains poorly und...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Li, Yixuan, Zhang, Xiangyang, Zhu, Shaoqi, Dejene, Eden A., Peng, Weiqun, Sepulveda, Antonia, Seto, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442594/
https://ncbi.nlm.nih.gov/pubmed/32540961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3613
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