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Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation

Poly(A)-specific ribonuclease (PARN) is a 3′-exoribonuclease that plays an important role in regulating the stability and maturation of RNAs. Recently, PARN has been found to regulate the maturation of the human telomerase RNA component (hTR), a noncoding RNA required for telomere elongation. Specif...

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Pubblicato in:J Biol Chem
Autori principali: Dejene, Eden A., Li, Yixuan, Showkatian, Zahra, Ling, Hongbo, Seto, Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383379/
https://ncbi.nlm.nih.gov/pubmed/32457045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012552
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