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HDAC10 Regulates Cancer Stem-like Cell Properties in KRAS-driven Lung Adenocarcinoma

Activation of oncogenic KRAS is the most common driving event in lung adenocarcinoma development. Despite the existing rationale for targeting activated KRAS and its downstream effectors, the failure of clinical trials to date indicates that the mechanism of KRAS-driven malignancy remains poorly und...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Li, Yixuan, Zhang, Xiangyang, Zhu, Shaoqi, Dejene, Eden A., Peng, Weiqun, Sepulveda, Antonia, Seto, Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442594/
https://ncbi.nlm.nih.gov/pubmed/32540961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3613
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