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Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation
BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment. Developing mouse models that accurately reflect each of these distinct features will be...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442382/ https://ncbi.nlm.nih.gov/pubmed/31638150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz197 |
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