Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment. Developing mouse models that accurately reflect each of these distinct features will be...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Patel, Smruti K, Hartley, Rachel M, Wei, Xin, Furnish, Robin, Escobar-Riquelme, Fernanda, Bear, Heather, Choi, Kwangmin, Fuller, Christine, Phoenix, Timothy N
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Pediatric Neuro-Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442382/
https://ncbi.nlm.nih.gov/pubmed/31638150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz197
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