Loading...

Determination of protein–ligand binding modes using fast multi-dimensional NMR with hyperpolarization

Elucidation of small molecule–protein interactions provides essential information for understanding biological processes such as cellular signaling, as well as for rational drug development. Here, multi-dimensional NMR with sensitivity enhancement by dissolution dynamic nuclear polarization (D-DNP)...

Full description

Saved in:
Bibliographic Details
Published in:Chem Sci
Main Authors: Wang, Yunyi, Kim, Jihyun, Hilty, Christian
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441707/
https://ncbi.nlm.nih.gov/pubmed/32874513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00266f
Tags: Add Tag
No Tags, Be the first to tag this record!