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Measuring protein stability in the GroEL chaperonin cage reveals massive destabilization
The thermodynamics of protein folding in bulk solution have been thoroughly investigated for decades. By contrast, measurements of protein substrate stability inside the GroEL/ES chaperonin cage have not been reported. Such measurements require stable encapsulation, that is no escape of the substrat...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7440923/ https://ncbi.nlm.nih.gov/pubmed/32716842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56511 |
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