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Probing Water Density and Dynamics in the Chaperonin GroEL Cavity

[Image: see text] ATP-dependent binding of the chaperonin GroEL to its cofactor GroES forms a cavity in which encapsulated substrate proteins can fold in isolation from bulk solution. It has been suggested that folding in the cavity may differ from that in bulk solution owing to steric confinement,...

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Autors principals: Franck, John M., Sokolovski, Miri, Kessler, Naama, Matalon, Erez, Gordon-Grossman, Michal, Han, Song-i, Goldfarb, Daniella, Horovitz, Amnon
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091268/
https://ncbi.nlm.nih.gov/pubmed/24888581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503501x
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