The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

Leprosy is a chronic disease caused by Mycobacterium leprae. Worldwide, more than 200,000 new patients are affected by leprosy annually, making it the second most common mycobacterial disease after tuberculosis. The MHC/HLA region has been consistently identified as carrying major leprosy susceptibi...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Dallmann-Sauer, Monica, Fava, Vinicius M., Gzara, Chaïma, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Schurr, Erwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440659/
https://ncbi.nlm.nih.gov/pubmed/32776973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008818
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