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Simvastatin induces adverse effects on proliferation and mineralization of human primary osteoblasts

BACKGROUND: Frequently statins were administered to reduce the LDL-concentration in circulating blood. Especially simvastatin (SV) is an often prescribed statin. Pleiotropic effects of these drugs were reported. Thus, the aim of this study was to evaluate effects of SV on osteoblastic mineralization...

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Detalhes bibliográficos
Publicado no:Head Face Med
Main Authors: Sabandal, Martin Mariano Isabelo, Schäfer, Edgar, Aed, Jonathan, Jung, Susanne, Kleinheinz, Johannes, Sielker, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439668/
https://ncbi.nlm.nih.gov/pubmed/32819403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13005-020-00232-4
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