Simvastatin induces adverse effects on proliferation and mineralization of human primary osteoblasts

BACKGROUND: Frequently statins were administered to reduce the LDL-concentration in circulating blood. Especially simvastatin (SV) is an often prescribed statin. Pleiotropic effects of these drugs were reported. Thus, the aim of this study was to evaluate effects of SV on osteoblastic mineralization...

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Опубликовано в: :Head Face Med
Главные авторы: Sabandal, Martin Mariano Isabelo, Schäfer, Edgar, Aed, Jonathan, Jung, Susanne, Kleinheinz, Johannes, Sielker, Sonja
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439668/
https://ncbi.nlm.nih.gov/pubmed/32819403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13005-020-00232-4
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