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Simvastatin induces adverse effects on proliferation and mineralization of human primary osteoblasts

BACKGROUND: Frequently statins were administered to reduce the LDL-concentration in circulating blood. Especially simvastatin (SV) is an often prescribed statin. Pleiotropic effects of these drugs were reported. Thus, the aim of this study was to evaluate effects of SV on osteoblastic mineralization...

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Bibliographische Detailangaben
Veröffentlicht in:Head Face Med
Hauptverfasser: Sabandal, Martin Mariano Isabelo, Schäfer, Edgar, Aed, Jonathan, Jung, Susanne, Kleinheinz, Johannes, Sielker, Sonja
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439668/
https://ncbi.nlm.nih.gov/pubmed/32819403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13005-020-00232-4
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