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Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations

Systemic antibodies targeting tumor necrosis factor–α (TNF-α) and interleukin-17A (IL-17A) are effective in plaque psoriasis. Despite their popularity, safety concerns pose a challenge for systemic biologics. While anti–TNF-α and anti–IL-17A antibodies effectively inhibit respective proteins, we hyp...

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Bibliografiska uppgifter
I publikationen:Sci Adv
Huvudupphovsmän: Mandal, Abhirup, Kumbhojkar, Ninad, Reilly, Charles, Dharamdasani, Vimisha, Ukidve, Anvay, Ingber, Donald E., Mitragotri, Samir
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association for the Advancement of Science 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439648/
https://ncbi.nlm.nih.gov/pubmed/32832675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb6049
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