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Development and Optimization of Nanosomal Formulations for siRNA Delivery to the Liver
The objective of this study is to develop an effective siRNA delivery system for successful delivery to the liver for the treatment of HCV. Nanosize liposomes (nanosomes) have been prepared using a mixture of cholesterol and DOTAP. A functional siRNA was encapsulated into nanosomes following condens...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298086/ https://ncbi.nlm.nih.gov/pubmed/22119665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2011.10.023 |
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